BDBM503407 (5M)-6-amino-2-[(4S)-4-amino-4- methylazepan-1-yl]-5-(2,3- dichlorophenyl)-pyrimidine-4- carboxamide::US11033547, Compound 110

SMILES C[C@]1(N)CCCN(CC1)c1nc(N)c(c(n1)C(N)=O)-c1cccc(Cl)c1Cl

InChI Key InChIKey=AURKNQJDGSCBLL-SFHVURJKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503407   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM503407((5M)-6-amino-2-[(4S)-4-amino-4- methylazepan-1-yl]...)
Affinity DataIC50:  4.40E+3nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent