BDBM503412 (4M)-2-(4-amino-4-methylpiperidin-1- yl)-5-(2-chloro-4-fluoro-3- methoxyphenyl)-6-methylpyrimidine-4- carboxamide::US11033547, Compound 115::US11033547, Compound 116::US11696916, Compound 116
SMILES COc1c(F)ccc(c1Cl)-c1c(C)nc(nc1C(N)=O)N1CCC(C)(N)CC1
InChI Key InChIKey=QVABOPWURJBUEO-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 503412
Affinity DataIC50: 570nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair