BDBM50341550 (E)-N-Ethyl-2-(1-(pyridin-2-yl)ethylidene)hydrazinecarbothioamide::2-acetylpyridine 4-ethyl-3-thiosemicarbazone::2-acetylpyridine N4(ethyl)thiosemicarbazone::CHEMBL507986

SMILES CCNC(=S)NN=C(C)c1ccccn1

InChI Key InChIKey=JTHKAYIQGRORJA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50341550   

TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50341550((E)-N-Ethyl-2-(1-(pyridin-2-yl)ethylidene)hydrazin...)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pHOT DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed