BDBM50341566 5-[7-Chloro-3-(3,5-dimethylphenyl)-4-{2-[(2R)-piperidin-2-yl]ethoxy}quinolin-6-yl]pyridin-2-amine::CHEMBL1766091

SMILES Cc1cc(C)cc(c1)-c1cnc2cc(Cl)c(cc2c1OCC[C@H]1CCCCN1)-c1ccc(N)nc1

InChI Key InChIKey=YSWXCSZXSAXHDX-JOCHJYFZSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341566   

TargetSomatostatin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50341566(5-[7-Chloro-3-(3,5-dimethylphenyl)-4-{2-[(2R)-pipe...)
Affinity DataKi:  0.600nMAssay Description:Displacement of I125-somatostatin-14 from human SST2 expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSomatostatin receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50341566(5-[7-Chloro-3-(3,5-dimethylphenyl)-4-{2-[(2R)-pipe...)
Affinity DataIC50:  34nMAssay Description:Agonist activity at human SST2 expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP release after 40 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed