BDBM50341679 4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine::6-(2-{6-[2-(2-amino-6-methylpyridin-4-yl)ethyl]pyridin-2-yl}ethyl)-4-methylpyridin-2-amine::CHEMBL1615291::NOS Inhibitor, 3m

SMILES Cc1cc(N)nc(CCc2cccc(CCc3cc(C)nc(N)c3)n2)c1

InChI Key InChIKey=ZMKGFXFDYMNDSP-UHFFFAOYSA-N

Data  6 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50341679   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  195nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  195nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  1.26E+4nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  1.26E+4nMAssay Description:Inhibition of mouse macrophage recombinant iNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
University Of California Irvine

LigandPNGBDBM50341679(4-(2-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyr...)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair