BDBM50342169 CHEMBL1766170::rac-1-(4'-Fluoro[1,1'-biphenyl]-3-yl)-1-(1H-imidazol-4-yl)-2-methyl-1-propanol

SMILES CC(C)C(O)(c1cnc[nH]1)c1cccc(c1)-c1ccc(F)cc1

InChI Key InChIKey=LOFFEKCUNLMSQZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342169   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rattus norvegicus (Rat))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342169(CHEMBL1766170 | rac-1-(4'-Fluoro[1,1'-biphenyl]-3-...)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of 17,20 lyase activity in Sprague-Dawley rat testicular microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342169(CHEMBL1766170 | rac-1-(4'-Fluoro[1,1'-biphenyl]-3-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human CYP3A4 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50342169(CHEMBL1766170 | rac-1-(4'-Fluoro[1,1'-biphenyl]-3-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human 17,20 lyase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed