BDBM50342301 2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-carboxamide::CHEMBL1767254

SMILES NC(=O)c1ccsc1NC(=O)Cc1csc2ccccc12

InChI Key InChIKey=ZZKGJVRSUVIYIJ-UHFFFAOYSA-N

Data  3 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342301   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to JNK1 in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of JNK1 by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataKd:  640nMAssay Description:Binding affinity to JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataIC50:  4.62E+3nMAssay Description:Displacement of biotin-labeled JIP1 peptide from JNK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTranscription factor Jun(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of TNFalpha-induced c-Jun phosphorylation in human HeLa cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50342301(2-(2-(benzo[b]thiophen-3-yl)acetamido)thiophene-3-...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to JNK1 in presence of peptide JIP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed