BDBM50343002 CHEMBL1770987::N2-cyclopentyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine

SMILES CN1CCN(CC1)c1cc(N)nc(NC2CCCC2)n1

InChI Key InChIKey=IGLCVBMHZYOWIQ-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343002   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50343002(CHEMBL1770987 | N2-cyclopentyl-6-(4-methylpiperazi...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50343002(CHEMBL1770987 | N2-cyclopentyl-6-(4-methylpiperazi...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells assessed as effect on forskolin-induced cAMP accumulation after 6 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed