BDBM50343012 CHEMBL1770962::N2-isopropyl-4-(4-methylpiperazin-1-yl)pyridine-2,6-diamine

SMILES CC(C)Nc1cc(cc(N)n1)N1CCN(C)CC1

InChI Key InChIKey=LUKSYCWZFMYISW-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343012   

TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50343012(CHEMBL1770962 | N2-isopropyl-4-(4-methylpiperazin-...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50343012(CHEMBL1770962 | N2-isopropyl-4-(4-methylpiperazin-...)
Affinity DataEC50:  533nMAssay Description:Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells assessed as effect on forskolin-induced cAMP accumulation after 6 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed