BDBM50343217 CHEMBL1773584::N-(6-(2-(Benzylthio)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide

SMILES CC(=O)Nc1nc2ccc(cc2s1)-c1ccnc(SCc2ccccc2)n1

InChI Key InChIKey=ZPONXRCXJFRAMU-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343217   

LigandPNGBDBM50343217(CHEMBL1773584 | N-(6-(2-(Benzylthio)pyrimidin-4-yl...)
Affinity DataKi:  47nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343217(CHEMBL1773584 | N-(6-(2-(Benzylthio)pyrimidin-4-yl...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed