BDBM50343235 CHEMBL1773077::N-(6-(2-(3-Methoxybenzyloxy)pyrimidin-4-yl)benzo[d]thiazol-2-yl)acetamide

SMILES COc1cccc(COc2nccc(n2)-c2ccc3nc(NC(C)=O)sc3c2)c1

InChI Key InChIKey=CAAPYGAYUZRWMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343235   

LigandPNGBDBM50343235(CHEMBL1773077 | N-(6-(2-(3-Methoxybenzyloxy)pyrimi...)
Affinity DataKi:  18nMAssay Description:Inhibition of human PI3Kalpha expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50343235(CHEMBL1773077 | N-(6-(2-(3-Methoxybenzyloxy)pyrimi...)
Affinity DataIC50: >6.00E+3nMAssay Description:Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed