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BDBM50345475 CHEMBL4175704

SMILES: Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=BMCWSRYOAAOTHK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345475   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein lin-28 homolog A


(Mus musculus)
BDBM50345475
PNG
(CHEMBL4175704)
Show SMILES Fc1ccc(cc1)S(=O)(=O)Nc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C18H14ClFN2O4S2/c19-13-5-9-15(10-6-13)27(23,24)21-17-3-1-2-4-18(17)22-28(25,26)16-11-7-14(20)8-12-16/h1-12,21-22H
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
PubMed
n/an/a 2.73E+4n/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to mouse N-terminal Halo-fused/biotin-labelled Lin28A expressed in Escherichia coli BL21(DE3) assessed as inhibition of protein inte...


ACS Med Chem Lett 9: 517-521 (2018)


BindingDB Entry DOI: 10.7270/Q24T6MXZ
More data for this
Ligand-Target Pair