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BDBM50347608 CHEMBL1802988

SMILES: FC(F)(F)c1ccc2c(c1)[nH]c1cccnc21

InChI Key: InChIKey=FUJRUJQSDDIUDN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50347608   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kinesin-like protein 1


(Homo sapiens)
BDBM50347608
PNG
(CHEMBL1802988)
Show SMILES FC(F)(F)c1ccc2c(c1)[nH]c1cccnc21
Show InChI InChI=1S/C12H7F3N2/c13-12(14,15)7-3-4-8-10(6-7)17-9-2-1-5-16-11(8)9/h1-6,17H
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 330n/an/an/an/an/an/a



Kyoto University

Curated by ChEMBL


Assay Description
Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assay


J Med Chem 54: 4839-46 (2011)


Article DOI: 10.1021/jm200448n
BindingDB Entry DOI: 10.7270/Q20V8D5G
More data for this
Ligand-Target Pair