BDBM50347614 CHEMBL1803018

SMILES NC(=O)Nc1ccc2[nH]c3cc(ccc3c2c1)C(F)(F)F

InChI Key InChIKey=HBPRRKVUKLLMDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347614   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347614(CHEMBL1803018)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-terminally His6-tagged microtubule-activated KSP motor domain ATPase activity after 15 mins by luciferase-derived luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50347614(CHEMBL1803018)
Affinity DataIC50:  120nMAssay Description:Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) expressed in bacteria incubated for 30 mins prior to ATP addition measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed