BDBM50350747 CHEMBL1818296
SMILES CN(C)CCC1CCN(CC1)c1cc(C(=O)NC[C@H]2CC[C@H](CNC(=O)OC(C)(C)C)CC2)c2ccccc2n1
InChI Key InChIKey=LPNMMJSQRBCMKX-SOAUALDESA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50350747
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant his-tagged ACC2 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant his-tagged ACC1 expressed in baculovirus/Sf9 cell assessed as inorganic phosphate formation preincubated for 15 mins ...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of obese Zucker rat ACC1 assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malachit...More data for this Ligand-Target Pair
TargetAcetyl-CoA carboxylase(Rattus norvegicus (Rat))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of ACC2 in obese Zucker rat assessed as reduction in hepatic malonyl-coA level preincubated for 15 mins measured after 1.5 hrs using Malac...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca Research And Development
Curated by ChEMBL
Astrazeneca Research And Development
Curated by ChEMBL
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair