BDBM50353044 CHEMBL1822523

SMILES COc1ccccc1-c1ccc2cnc(Nc3ccc(cc3OC)N3CCN(CC3)N3CCN(C)CC3)nn12

InChI Key InChIKey=DCQGBFHFVFACQU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50353044   

TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353044(CHEMBL1822523)
Affinity DataIC50:  70nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353044(CHEMBL1822523)
Affinity DataIC50:  266nMAssay Description:Inhibition of IRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353044(CHEMBL1822523)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of human recombinant ALK assessed as phosphorylated product using PLC-gamma/GST substrate by modified ELISA methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed