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BDBM50353477 CHEMBL1830277

SMILES: NC(=S)NN=C(C=Cc1ccccc1)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=YCDLIADNLQNFRV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50353477   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM50353477
PNG
(CHEMBL1830277)
Show SMILES NC(=S)NN=C(C=Cc1ccccc1)c1ccc(Cl)c(Cl)c1
Show InChI InChI=1S/C16H13Cl2N3S/c17-13-8-7-12(10-14(13)18)15(20-21-16(19)22)9-6-11-4-2-1-3-5-11/h1-10H,(H3,19,21,22)
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 9.78E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged EGFR expressed in insect Sf9 cells after 1 hr by time-resolved fluorimetric analysis


Eur J Med Chem 46: 4702-8 (2011)


Article DOI: 10.1016/j.ejmech.2011.07.016
BindingDB Entry DOI: 10.7270/Q28S4Q8T
More data for this
Ligand-Target Pair