BDBM50353589 CHEMBL1828979
SMILES Cc1noc(C)c1-c1ccccc1
InChI Key InChIKey=BHAXDAUULXCVEK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50353589
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of BRD4 (unknown origin) by biotinylated-JQ1 based AlphaScreen BRD binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.43E+4nMAssay Description:Displacement of H4Ac4 peptide from first bromodomain of human BRD2 by peptide displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+5nMAssay Description:Displacement of H3K56Ac from human CREBBP by peptide displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Displacement of FITC-labeled (+)-JQ1 from bromodomain BRD4(1) (unknown origin) expressed in Escherichia coli BL21(DE3) after 4 hrs by fluorescence an...More data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Binding affinity to human His-tagged bromodomain BRD4(1) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) measured by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.42E+4nMAssay Description:Displacement of H4Ac4 peptide from first bromodomain of human BRD4 by peptide displacement assayMore data for this Ligand-Target Pair