BDBM50353868 CHEMBL1830873::US9006187, 4

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1cc(Cc2ccc(OCC=C)cc2)c(Cl)s1

InChI Key InChIKey=DBHDSGVPTUJUNY-FTWQHDNSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353868   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50353868(CHEMBL1830873 | US9006187, 4)
Affinity DataIC50:  54.6nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50353868(CHEMBL1830873 | US9006187, 4)
Affinity DataIC50:  54.6nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent