BDBM50353888 CHEMBL1829084::US9006187, 27
SMILES Cc1cc(sc1Cc1ccc(cc1)C(C)(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
InChI Key InChIKey=JRMIAXVGZDIABG-GRARQNNCSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50353888
Affinity DataIC50: 88.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 88.3nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair