BDBM50353888 CHEMBL1829084::US9006187, 27

SMILES Cc1cc(sc1Cc1ccc(cc1)C(C)(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=JRMIAXVGZDIABG-GRARQNNCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50353888   

TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50353888(CHEMBL1829084 | US9006187, 27)
Affinity DataIC50:  88.3nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 2(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50353888(CHEMBL1829084 | US9006187, 27)
Affinity DataIC50:  88.3nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In DepthDetails US Patent