BDBM50354498 CHEMBL1836792

SMILES Fc1ccc2NC(=O)C(CCCCN3CCC(=CC3)c3cccc(c3)C(F)(F)F)c2c1

InChI Key InChIKey=AFFLRZAJRVFCHF-UHFFFAOYSA-N

Data  2 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50354498   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
EGIS Pharmaceuticals Plc

Curated by ChEMBL
LigandPNGBDBM50354498(CHEMBL1836792)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCC(=CC3)c3cccc(c3)C(F)(F)F)c2c1
Show InChI InChI=1S/C24H24F4N2O/c25-19-7-8-22-21(15-19)20(23(31)29-22)6-1-2-11-30-12-9-16(10-13-30)17-4-3-5-18(14-17)24(26,27)28/h3-5,7-9,14-15,20H,1-2,6,10-13H2,(H,29,31)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
EGIS Pharmaceuticals Plc

Curated by ChEMBL
LigandPNGBDBM50354498(CHEMBL1836792)
Show SMILES Fc1ccc2NC(=O)C(CCCCN3CCC(=CC3)c3cccc(c3)C(F)(F)F)c2c1
Show InChI InChI=1S/C24H24F4N2O/c25-19-7-8-22-21(15-19)20(23(31)29-22)6-1-2-11-30-12-9-16(10-13-30)17-4-3-5-18(14-17)24(26,27)28/h3-5,7-9,14-15,20H,1-2,6,10-13H2,(H,29,31)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat frontal cortex membrane after 45 mins by scintillation countingMore data for this Ligand-Target Pair