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BDBM50356254 CHEMBL1910685

SMILES: C\N=C1/S\C(=C/c2cc(C)n(c2C)-c2ncccc2F)C(=O)N1C

InChI Key: InChIKey=XXXKEHADQYSTNX-YPFSYJIWSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50356254   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sphingosine 1-phosphate receptor 4


(Homo sapiens (Human))
BDBM50356254
PNG
(CHEMBL1910685)
Show SMILES C\N=C1/S\C(=C/c2cc(C)n(c2C)-c2ncccc2F)C(=O)N1C
Show InChI InChI=1S/C17H17FN4OS/c1-10-8-12(9-14-16(23)21(4)17(19-3)24-14)11(2)22(10)15-13(18)6-5-7-20-15/h5-9H,1-4H3/b14-9-,19-17-
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 3.10E+3n/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein asses...


Bioorg Med Chem Lett 21: 6739-45 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.049
BindingDB Entry DOI: 10.7270/Q2736RBP
More data for this
Ligand-Target Pair