BDBM50357187 CHEMBL1914576
SMILES [#6]-[#6]1=[#6](C#N)\[#6](-[#8]C1([#6])c1ccc(Cl)c(Cl)c1)=[#6](\C#N)C#N
InChI Key InChIKey=RSWZFAPYKOARNG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50357187
Affinity DataKi: 655nMAssay Description:Displacement of [3H]PSB-13253 from human recombinant GPR35 exprssed in CHO cells by liquid scintillation counting analysisChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as desensitization of 1 uM zaprinast-induced DMR after 1 hr by dynamic mass redistribution as...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at GPR35 in human HT-29 cells assessed as induction of cell desensitization to 1 uM zaprinast preincubated for 1 hr followed by zapr...More data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.02E+4nMAssay Description:Agonist activity at GPR35 in human U20S cells expressing beta-lactamase and GPR35-GA14-VP16 transcription factor fusion protein assessed as transcrip...More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Agonist activity at GPR35 in human HT-29 cells after 1 hr by dynamic mass redistribution assayMore data for this Ligand-Target Pair