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BDBM50357372 CHEMBL1917263

SMILES: Cc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1

InChI Key: InChIKey=HQSNWLKMWUNTEZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50357372   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50357372
PNG
(CHEMBL1917263)
Show SMILES Cc1ccc(CSc2nnc(o2)-c2ccc3OCCOc3c2)cc1
Show InChI InChI=1S/C18H16N2O3S/c1-12-2-4-13(5-3-12)11-24-18-20-19-17(23-18)14-6-7-15-16(10-14)22-9-8-21-15/h2-7,10H,8-9,11H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 5.04E+3n/an/an/an/an/an/a



Nanjing University

Curated by ChEMBL


Assay Description
Inhibition of telomerase in human SW1116 cells after 24 hrs by TRAP-PCR-ELISA assay


Bioorg Med Chem 19: 6518-24 (2011)


Article DOI: 10.1016/j.bmc.2011.08.013
BindingDB Entry DOI: 10.7270/Q2H70G7M
More data for this
Ligand-Target Pair