BDBM50357489 CHEMBL1914472
SMILES CCC(C)[C@]1(CCN([C@@H](CCc2ccccc2)C(=O)N[C@@H](Cc2cc(F)cc(F)c2)[C@H](O)CNCc2cccc(OC)c2)C1=O)NC(C)=O
InChI Key InChIKey=RCAZOLSIRITUKZ-VHVJLOLGSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50357489
Affinity DataIC50: 6.10nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by ELI...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]BMS-599240 from recombinant human BACE-1More data for this Ligand-Target Pair