BDBM50357706 CHEMBL1915976

SMILES COc1cccc(CNC[C@@H](O)[C@H](Cc2cc(F)cc(F)c2)NC(=O)[C@H](CCc2ccccc2)N2CC[C@H](CC(C)C)C2=O)c1

InChI Key InChIKey=SNDXBLGCUUUDPP-XZLGBSMGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357706   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357706(CHEMBL1915976)
Affinity DataIC50:  240nMAssay Description:Inhibition of BACE1 in human HEK293 cells expressing swedish mutant APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50357706(CHEMBL1915976)
Affinity DataIC50:  20nMAssay Description:Inhibition of BACE1 by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed