BDBM50357884 CHEMBL1916359

SMILES [O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1Cl

InChI Key InChIKey=AUZOBOALIFKXNA-UHFFFAOYSA-N

Data  55 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 55 hits for monomerid = 50357884   

TargetSerine/threonine-protein kinase D2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human TrkBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CHK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MAPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SAPK2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cKitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human c-RAFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human cSRCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DYRK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EphA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EphB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Flt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeodomain-interacting protein kinase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HIPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IKK-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human IRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JNK1alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JNK2alpha2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MAPK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MAPKAP-K2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MLCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Mnk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MSK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human AblMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ALKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 5(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ASK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BTKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase type IV(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CaMK4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CDK6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform gamma-1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CK1gamma1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CK1deltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50:  14nMAssay Description:Inhibition of human p38alpha MAP kinase after 1 hr by FRET analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Nek2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human NEK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Pim-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PKBalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PRAKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human PRK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human RIPK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Rsk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SAPK2bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50357884(CHEMBL1916359)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human SAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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