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BDBM50358578 CHEMBL1923739

SMILES: C[C@@H]1CCCN1CCCOc1cccc(c1)-c1ccc(=O)n(C)c1

InChI Key: InChIKey=QSMYFYVFZBONDI-MRXNPFEDSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358578   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))
BDBM50358578
PNG
(CHEMBL1923739)
Show SMILES C[C@@H]1CCCN1CCCOc1cccc(c1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H26N2O2/c1-16-6-4-11-22(16)12-5-13-24-19-8-3-7-17(14-19)18-9-10-20(23)21(2)15-18/h3,7-10,14-16H,4-6,11-13H2,1-2H3/t16-/m1/s1
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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
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Similars

Article
PubMed
112n/an/an/an/an/an/an/an/a



Cephalon Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 21: 7076-80 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.091
BindingDB Entry DOI: 10.7270/Q26H4HVK
More data for this
Ligand-Target Pair
Histamine H3 receptor


(Rattus norvegicus (rat))
BDBM50358578
PNG
(CHEMBL1923739)
Show SMILES C[C@@H]1CCCN1CCCOc1cccc(c1)-c1ccc(=O)n(C)c1
Show InChI InChI=1S/C20H26N2O2/c1-16-6-4-11-22(16)12-5-13-24-19-8-3-7-17(14-19)18-9-10-20(23)21(2)15-18/h3,7-10,14-16H,4-6,11-13H2,1-2H3/t16-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>500n/an/an/an/an/an/an/an/a



Cephalon Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells


Bioorg Med Chem Lett 21: 7076-80 (2011)


Article DOI: 10.1016/j.bmcl.2011.09.091
BindingDB Entry DOI: 10.7270/Q26H4HVK
More data for this
Ligand-Target Pair