BDBM50358743 CHEMBL1922270
SMILES C[C@@H]1[C@H]2CN(CCCC3CCOCC3)CC[C@@H]2Cc2[nH]c3ccc(cc3c12)C(F)(F)F
InChI Key InChIKey=VGWOOKCYUNUQRH-HGHGUNKESA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50358743
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human MCHR1 expressed in Jurkat cells co-expressing apoaequorin assessed as inhibition of MCH-induced calcium mobilization by ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by beta scintillation countingMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of human Erg expressed in HEK293 cells assessed as rubidium efflux after 4 hrs by atomic absorbance spectrometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at cynomolgus monkey MCHR1More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Displacement of [125I]-MCH from MCHR1 after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Antagonist activity at rat MCHR1 expressed in HEK293 cells by aequorin bioluminescence assayMore data for this Ligand-Target Pair