BDBM50359500 (R)Methamphetamine::CHEMBL1927030

SMILES CN[C@H](C)Cc1ccccc1

InChI Key InChIKey=MYWUZJCMWCOHBA-SECBINFHSA-N

Data  2 KI  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50359500   

TargetAmine oxidase [flavin-containing] B(Rat)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataKi:  5.50E+5nMAssay Description:Competitive inhibition of Rat liver Monoamine Oxidase B at 37 degree C (pH= 7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Bovine)
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataKi:  8.00E+5nMAssay Description:Inhibitory activity against Monoamine Oxidase B of Bovine liver in competitive inhibition assay at 25 degree C (pH=7.4)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  1.19E+3nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of mouse TAAR1 transmembrane domain 7 Tyr287(7.39)Asn mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  1.11E+3nMAssay Description:Activation of rat TAAR1 transmembrane domain 6 Met268(6.55)Thr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  233nMAssay Description:Activation of rat wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  330nMAssay Description:Activation of rat TAAR1 transmembrane domain 7 Asn287(7.39)Tyr mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  126nMAssay Description:Activation of mouse TAAR1 transmembrane domain 6 Thr268(6.55)Met mutant expressed in HEK293 cells assessed as stimulation of cAMP production after 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  843nMAssay Description:Activation of mouse wild type TAAR1 expressed in HEK293 cells assessed as stimulation of cAMP production after 1 hr by chemiluminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrace amine-associated receptor 1(Mouse)
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50359500((R)Methamphetamine | CHEMBL1927030)
Affinity DataEC50:  2.44E+3nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed