BDBM503611 2-(3-(4-(4-fluorophenyl)-3,6-dihydropyridin-1 (2H)-yl)-3-oxopropyl)quinazolin-4 (3H)-one::US11034670, Ex. 51

SMILES Fc1ccc(cc1)C1=CCN(CC1)C(=O)CCc1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=OVXXLTCZEHZISR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 503611   

TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM503611(2-(3-(4-(4-fluorophenyl)-3,6-dihydropyridin-1 (2H)...)
Affinity DataIC50:  339nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Mitobridge

US Patent
LigandPNGBDBM503611(2-(3-(4-(4-fluorophenyl)-3,6-dihydropyridin-1 (2H)...)
Affinity DataIC50:  83nMAssay Description:The scintillation proximity assay (SPA) is designed to measure PARP activity using purified recombinant PARP-1 enzyme and is ideal for high throughpu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent