BDBM50361475 CHEMBL1938900

SMILES ON(CCCCNCc1ccc(COC(=O)Nc2cccc3ccccc23)cc1)C(=O)C=CC(O)=O

InChI Key InChIKey=FOJNYQXAAPCEPX-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50361475   

TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of KDM4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of KDM4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  8.30E+4nMAssay Description:Inhibition of PHD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of FIHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  5.40E+4nMAssay Description:Inhibition of PHD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of KDM6BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of JMJD2A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN3(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of PHD3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of JMJD2AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of JMJD2EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of N-terminal GST-fused human JMJD2C catalytic domain amino acid 1 to 420 using H3K9me3 as substrate by mass spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of recombinant 6xHis-tagged JMJD3 (unknown origin) expressed in Escherichia coli BL21More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine

Curated by ChEMBL
LigandPNGBDBM50361475(CHEMBL1938900)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of KDM7BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed