BDBM50362853 CHEMBL1940408

SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=ARWONURFSGKTJW-UHFFFAOYSA-N

Data  12 KI

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50362853   

TargetD(4) dopamine receptor(RAT)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(RAT)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]N-methylspiperone from rat dopamine D4 receptor by PDSP assayMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  36nMAssay Description:Displacement [3H]-Pentazocine from sigma 1 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  52nMAssay Description:Displacement [3H]-DTG from sigma 2 receptor (unknown origin) expressed in HEK cell membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DOI from human 5HT2A receptor after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  112nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  261nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by PDSP assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  261nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  284nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by liquid scintillation countingMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  284nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor by PDSP assayMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  589nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor by PDSP assayMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50362853(CHEMBL1940408)
Show SMILES Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C20H24ClFN2/c21-18-6-10-20(11-7-18)24-15-13-23(14-16-24)12-2-1-3-17-4-8-19(22)9-5-17/h4-11H,1-3,12-16H2
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor by PDSP assayMore data for this Ligand-Target Pair