BDBM50364339 CHEMBL1950085
SMILES Cc1n[nH]c2nc3c(C)cc(Cl)cc3c(C(O)c3ccncc3)c12
InChI Key InChIKey=CPFAZCJKWPHSEL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50364339
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of human recombinant PDE10A assessed as hydrolysis of cAMP to AMP using [3H]cAMP substrate by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Reversible inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Time dependent inhibition of CYP3A4More data for this Ligand-Target Pair