BDBM50367952 CHEMBL1628258::N-Desmethylvenlafaxine

SMILES CNCC(c1ccc(OC)cc1)C1(O)CCCCC1

InChI Key InChIKey=MKAFOJAJJMUXLW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50367952   

TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367952(CHEMBL1628258 | N-Desmethylvenlafaxine)
Affinity DataIC50:  300nMAssay Description:Inhibition of binding of [3H]imipramine to imipramine receptor in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367952(CHEMBL1628258 | N-Desmethylvenlafaxine)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of uptake of tritiated norepinephrine (NE) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50367952(CHEMBL1628258 | N-Desmethylvenlafaxine)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of uptake of tritiated serotonin (5-HT) into rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed