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BDBM50368231 CHEMBL337134

SMILES: C[C@@H](CN1CCOCC1)n1c(C)c(C(=O)c2ccccc2F)c2ccccc12

InChI Key: InChIKey=COEIKTDOBBJAHE-INIZCTEOSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368231   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50368231
PNG
(CHEMBL337134)
Show SMILES C[C@@H](CN1CCOCC1)n1c(C)c(C(=O)c2ccccc2F)c2ccccc12
Show InChI InChI=1S/C23H25FN2O2/c1-16(15-25-11-13-28-14-12-25)26-17(2)22(19-8-4-6-10-21(19)26)23(27)18-7-3-5-9-20(18)24/h3-10,16H,11-15H2,1-2H3/t16-/m0/s1
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 8.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair