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BDBM50368234 CHEMBL1907835

SMILES: C[C@H](CN1CCOCC1)n1cc(C(=O)c2ccccc2F)c2ccccc12

InChI Key: InChIKey=YXWSEKFRRDMPBM-MRXNPFEDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50368234   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Prostaglandin-H2 D-isomerase


(Mus musculus)
BDBM50368234
PNG
(CHEMBL1907835)
Show SMILES C[C@H](CN1CCOCC1)n1cc(C(=O)c2ccccc2F)c2ccccc12
Show InChI InChI=1S/C22H23FN2O2/c1-16(14-24-10-12-27-13-11-24)25-15-19(17-6-3-5-9-21(17)25)22(26)18-7-2-4-8-20(18)23/h2-9,15-16H,10-14H2,1H3/t16-/m1/s1
PDB
MMDB

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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 9.00E+3n/an/an/an/an/an/a



Sterling Research Group

Curated by ChEMBL


Assay Description
Concentration required to inhibit 50% activity of prostaglandin synthetase was determined in vitro in mouse brain microsomes


J Med Chem 34: 1099-110 (1991)


Article DOI: 10.1021/jm00107a034
BindingDB Entry DOI: 10.7270/Q24M955S
More data for this
Ligand-Target Pair