BDBM50369382 CHEMBL1788223
SMILES COc1ccccc1N1CCN(C[C@H]2CN=C3N2C(SC)=Nc2ccccc32)CC1
InChI Key InChIKey=DVYBIZHLZSDANU-QGZVFWFLSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50369382
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]prazosin from Alpha-1A adrenergic receptorof rat submaxillary gland membranesMore data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]prazosin from Alpha-1B adrenergic receptor of rat liver membraneMore data for this Ligand-Target Pair
TargetHistamine H1 receptor(Cavia porcellus (domestic guinea pig))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: >50nMAssay Description:Compound is evaluated for binding affinity towards Histamine H1 receptor using [3H]pyrilamine in guinea pig lung at 10 uMMore data for this Ligand-Target Pair
Affinity DataKi: >50nMAssay Description:Compound is evaluated for binding affinity towards recombinant human Dopamine receptor D3 using [3H]spiperone in CHO cells at 10 uMMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 237nMAssay Description:Compound is evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]-8-OH- -DPAT in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataKi: 376nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2B adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 449nMAssay Description:Compound is evaluated for binding affinity towards Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 449nMAssay Description:Compound is evaluated for binding affinity towards Dopamine receptor D2 using [3H]spiperone in CHO cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Taiwan University
Curated by ChEMBL
National Taiwan University
Curated by ChEMBL
Affinity DataKi: 451nMAssay Description:Compound is evaluated for binding affinity towards Sigma receptor using [3H]pentazocine in guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 872nMAssay Description:Compound is evaluated for binding affinity towards Alpha-2A adrenergic receptor using [3H]prazosinMore data for this Ligand-Target Pair