BindingDB logo
myBDB logout

BDBM50370792 CHEMBL222114

SMILES: COc1ccc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)cc1

InChI Key: InChIKey=PUDPFAQGRSUVMS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370792   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Egl nine homolog 1


(Homo sapiens (Human))
BDBM50370792
PNG
(CHEMBL222114)
Show SMILES COc1ccc(COCc2ccc(nc2)-n2cc(cn2)C(O)=O)cc1
Show InChI InChI=1S/C18H17N3O4/c1-24-16-5-2-13(3-6-16)11-25-12-14-4-7-17(19-8-14)21-10-15(9-20-21)18(22)23/h2-10H,11-12H2,1H3,(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.40E+3n/an/an/an/an/an/a



Procter and Gamble Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Inhibition of human EGLN1


Bioorg Med Chem Lett 16: 5687-90 (2006)


Article DOI: 10.1016/j.bmcl.2006.08.017
BindingDB Entry DOI: 10.7270/Q25Q4WXS
More data for this
Ligand-Target Pair