BDBM50371492 CHEMBL256585

SMILES CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(CCS(=O)(=O)CC)C(=O)Cc1ccc(OC(F)(F)F)cc1)-c1ccccc1

InChI Key InChIKey=AIFWQRPYGQNPEW-HSZRJFAPSA-N

Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371492   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50371492(CHEMBL256585)
Show SMILES CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(CCS(=O)(=O)CC)C(=O)Cc1ccc(OC(F)(F)F)cc1)-c1ccccc1
Show InChI InChI=1S/C32H34F3N3O5S/c1-4-42-27-17-13-26(14-18-27)38-22-29(25-9-7-6-8-10-25)36-31(38)23(3)37(19-20-44(40,41)5-2)30(39)21-24-11-15-28(16-12-24)43-32(33,34)35/h6-18,22-23H,4-5,19-21H2,1-3H3/t23-/m1/s1
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasmaMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50371492(CHEMBL256585)
Show SMILES CCOc1ccc(cc1)-n1cc(nc1[C@@H](C)N(CCS(=O)(=O)CC)C(=O)Cc1ccc(OC(F)(F)F)cc1)-c1ccccc1
Show InChI InChI=1S/C32H34F3N3O5S/c1-4-42-27-17-13-26(14-18-27)38-22-29(25-9-7-6-8-10-25)36-31(38)23(3)37(19-20-44(40,41)5-2)30(39)21-24-11-15-28(16-12-24)43-32(33,34)35/h6-18,22-23H,4-5,19-21H2,1-3H3/t23-/m1/s1
Affinity DataIC50: 7.10nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair