BDBM50371510 CHEMBL270591

SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)C1CC1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F

InChI Key InChIKey=DIIYNJJEHJXNPJ-GOSISDBHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50371510   

TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50371510(CHEMBL270591)
Affinity DataIC50:  6.60nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50371510(CHEMBL270591)
Affinity DataIC50:  37nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed