BDBM50372712 CHEMBL271099

SMILES CNc1ncc(C(=O)Nc2cc(ccc2C)C(=O)Nc2cccc(c2)C(F)(F)F)c(Oc2ccccc2)n1

InChI Key InChIKey=GSKDHAVJCUTIGZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50372712   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of Jak3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50372712(CHEMBL271099)
Affinity DataIC50:  25nMAssay Description:Inhibition of Lck by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed