BDBM50374060 CHEMBL272267

SMILES Cn1c2cc(C(=O)NCCN3CCCC3)c(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1Cl

InChI Key InChIKey=LFRLUVCEFWYSFT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374060   

TargetWee1-like protein kinase(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL

LigandBDBM50374060(CHEMBL272267)Copy SMILESCopy InChI

Affinity DataIC50:  15nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL

LigandBDBM50374060(CHEMBL272267)Copy SMILESCopy InChI

Affinity DataIC50:  242nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI