BDBM50374598 CHEMBL272603::US9604926, Compound CM-156::US9724435, Compound CM-156

SMILES S=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1

InChI Key InChIKey=FJGOTAJCEJCFEV-UHFFFAOYSA-N

Data  16 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50374598   

TargetSigma intracellular receptor 2(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  0.550nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  0.550nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.28nMAssay Description:Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.28nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.28nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H](+)-pentazocine from sigma1 receptor in rat brain homogenate after 120 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H](-)-sulpiride from dopamine D2 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.04E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.18E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [3H]WIN-35428 from dopamine transporter in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.40E+3nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMu-type opioid receptor(Homo sapiens (Human))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus)
The University Of Mississippi

Curated by PDSP Ki Database
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(RAT)
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent