BDBM50375296 CHEMBL258704

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2s1

InChI Key InChIKey=AWMRTINMSUQIBM-ZCYQVOJMSA-N

Data  2 KI  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375296   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375296(CHEMBL258704)
Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2s1
Show InChI InChI=1S/C29H30N4O3S/c1-17-11-21(34)12-18(2)22(17)14-23(30)29(36)33-16-20-8-4-3-7-19(20)13-25(33)28(35)31-15-27-32-24-9-5-6-10-26(24)37-27/h3-12,23,25,34H,13-16,30H2,1-2H3,(H,31,35)/t23-,25-/m0/s1
Affinity DataKi:  0.145nMAssay Description:Binding affinity to delta opioid receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375296(CHEMBL258704)
Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2s1
Show InChI InChI=1S/C29H30N4O3S/c1-17-11-21(34)12-18(2)22(17)14-23(30)29(36)33-16-20-8-4-3-7-19(20)13-25(33)28(35)31-15-27-32-24-9-5-6-10-26(24)37-27/h3-12,23,25,34H,13-16,30H2,1-2H3,(H,31,35)/t23-,25-/m0/s1
Affinity DataKi:  1.06nMAssay Description:Binding affinity to mu opioid receptor in Sprague-Dawley rat brain membraneMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(GUINEA PIG)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50375296(CHEMBL258704)
Show SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCc1nc2ccccc2s1
Show InChI InChI=1S/C29H30N4O3S/c1-17-11-21(34)12-18(2)22(17)14-23(30)29(36)33-16-20-8-4-3-7-19(20)13-25(33)28(35)31-15-27-32-24-9-5-6-10-26(24)37-27/h3-12,23,25,34H,13-16,30H2,1-2H3,(H,31,35)/t23-,25-/m0/s1
Affinity DataIC50: 129nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of electrically-stimulated Hartely guinea pig contractionMore data for this Ligand-Target Pair