BDBM50375642 CHEMBL406381::KRN-633

SMILES CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl

InChI Key InChIKey=VPBYZLCHOKSGRX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50375642   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  170nMAssay Description:Inhibition of VEGFR1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  1nMAssay Description:Inhibition of human VEGFR1 in HUVEC cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  160nMAssay Description:Inhibition of VEGFR2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  1nMAssay Description:Inhibition of human VEGFR2 in HUVEC cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  970nMAssay Description:Inhibition of PDGFRalphaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  4.33E+3nMAssay Description:Inhibition of c-kitChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375642(CHEMBL406381 | KRN-633)
Affinity DataIC50:  125nMAssay Description:Inhibition of VEGFR3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed