BDBM50375645 CHEMBL219301::US11542290, Compound A-3

SMILES NCCNS(=O)(=O)c1cccc2c(Cl)cccc12

InChI Key InChIKey=ACIMRXKJKQGBGL-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375645   

TargetMyosin light chain kinase, smooth muscle(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375645(CHEMBL219301 | US11542290, Compound A-3)
Affinity DataKi:  7.40E+3nMAssay Description:Inhibition of myosin light chain kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50375645(CHEMBL219301 | US11542290, Compound A-3)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of casein kinase 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalmodulin-1(Human)
Camp4 Therapeutics

US Patent
LigandPNGBDBM50375645(CHEMBL219301 | US11542290, Compound A-3)
Affinity DataIC50:  2.41E+4nMAssay Description:The competition binding assay was performed in a 384-well plate format and in 20 μl reactions. Serial dilutions (0.001-100 μM) of a test co...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily B member 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50375645(CHEMBL219301 | US11542290, Compound A-3)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of voltage-gated potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed