BDBM50376467 CHEMBL260636
SMILES Fc1ccccc1-c1ccc2N=C(CC(=O)Nc2c1)c1cccc(c1)-n1ccnc1
InChI Key InChIKey=DWHFXDLHZUPSDA-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50376467
Affinity DataIC50: 27nMAssay Description:Antagonist activity at rat mGluR2 assessed as blockade of (1S,3R)-ACPD-induced inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat mGluR2 expressed in CHO cells assessed as inhibition of glutamta-induced GIRK currentMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
F. Hoffmann-La Roche
Curated by ChEMBL
F. Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Antagonist activity at rat mGluR3 expressed in CHO cells assessed as inhibition of glutamate-induced GIRK currentMore data for this Ligand-Target Pair