BDBM50378584 STEPHOLIDINE
SMILES COc1cc2CCN3Cc4c(C[C@H]3c2cc1O)ccc(O)c4OC
InChI Key InChIKey=JKPISQIIWUONPB-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 24 hits for monomerid = 50378584
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor expressed in HEKT cell membranes after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.90nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.23nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]SCH23390 from D1 receptor (unknown origin) transfected in HEK293T cells after 50 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Binding affinity to dopamine D3 receptor (unknown origin) by PDSP assayMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEKT cell membranes after 90 mins by microbeta scintillation counting metho...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 56.2nMAssay Description:Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [3H]Spiperone from D3 receptor (unknown origin) transfected in HEK293T cells after 50 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Displacement of [3H]Spiperone from D2 receptor (unknown origin) transfected in HEK293T cells after 50 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 974nMAssay Description:Displacement of [3H]spiperone from human dopamine D2L receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 974nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEKT cell membranes after 90 mins by microbeta scintillation counting metho...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 2.24E+3nMAssay Description:Displacement of [125I]-BE2254 from Wistar rat alpha1A adrenoceptor after 20 minsMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Friedrich-Schiller-Universit£T Jena
Curated by ChEMBL
Affinity DataKi: 3.75E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D4 receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counterMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of tissue factor procoagulant activity in LPS-stimulated human THP1 cells preincubated for 1 hr before LPS addition measured after 5 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.38E+3nMAssay Description:Antagonist activity at D2 receptor (unknown origin) after 40 mins by [35S]GTP-gammaS binding assay in presence of quinpiroleMore data for this Ligand-Target Pair
Affinity DataEC50: 4.11E+4nMAssay Description:Agonist activity at D1 receptor in rat striatum assessed as synaptosomal adenylate cyclase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 12.3nMAssay Description:Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 23nMAssay Description:Agonist activity at D1 receptor (unknown origin) after 40 mins by [35S]GTP-gammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Displacement of [3H]Spiprone from human dopamine D2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair