BDBM503795 3-(4-Ethylpyridin-3-yl)-N6-(1-piperidin-4- yl-1H-pyrazol-4-yl)-[2,7]naphthyridine- 1,6-diamine::US11034692, Compound 78

SMILES CCc1ccncc1-c1cc2cc(Nc3cnn(c3)C3CCNCC3)ncc2c(N)n1

InChI Key InChIKey=YROKYYVHWHBLSC-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503795   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM503795(3-(4-Ethylpyridin-3-yl)-N6-(1-piperidin-4- yl-1H-p...)
Affinity DataKi:  0.100nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent